Some scans do also target the installer files of problems detected by Spybot-S&D. Installers that the user must explicitely download himself will only be scanned for in the directories entered into this list.

You can either use Drag and Drop to drop some directories from an Explorer window or use the context menu to add or remove directories to or from the list.

You will find the download directories settings by choosing Directories from the Settings section in the toolbar to the left.